Department News

[기계전공대학원 세미나]정의헌교수(GIST)-초록 수정

Seminar Date 2011-11-21
Author
박지혜
Date
2011-11-21
Views
1658
1. 제 목 : Biophotonic microscopy towards super-resolution imaging for
cancer research
2. 연 사 : 정 의 헌 교수(GIST)
3. 일 시 : 2011년 11월 25일 (금) 16:30-17:30
4. 장 소 : 301동 105호
5. 연사약력 :
Euiheon Chung, PhD, is an Assistant Professor of the Graduate-program of Medical System
Engineering and School of Mechatronics at the Gwangju Institute of Science and
Technology (GIST). After receiving B.S. and M.S. degrees from Korea Advanced Institute of
Science and Technology (KAIST), Dr. Chung gained his PhD from the HarvardDivision
of Health Sciences and Technology (HST) Medical Engineering and Medical Physics
program in 2007. His work involved in the invention of supermicroscopy
techniques. While in graduate school, he helped a biotechnology startcompany,
Nanopoint Inc., as a technical consultant for the development of highimaging
system based on his graduate work. In addition, he also worked for a medical venture
company, Cambridge Devices Inc., to develop polarizationfluorescence imaging for
skin cancer detection. Since then he joined the Steele laboratory of Tumor Biology at
Massachusetts General Hospital and Harvard Medical School as a post-doc. His research
focuses on the creation of translational imaging technologies beyond proof
prototypes based on thorough understanding of the biological context and clinical needs.
6. 내용 :
Optical imaging has been an indispensable tool in biomedical research. In vivo imaging of small animals bearing tumor offers a unique opportunity to study cancer biology with
controlled model system. In this talk I illustrate the utilization of novel optical technologies for cancer detection and imaging complex cellular behaviors of cancer in vivo at various
scales. At the molecular scale, I describe the development of super-resolution microscopy
based on the application of standing waves(SW) with total internal reflection geometry and surface plasmon resonance (SPR) to amplify signals by electromagnetic field enhancement. The combination of these modalities resulted in a novel high-resolution microscopic
technique, standing-wave surface plasmon resonance fluorescence (SW-SPRF) microscopy. At the cellular scale, I introduce video-rate two-photon microscopy and a novel confocal
endomicroscopy to visualize the dynamic nature of tumor vasculature in a mouse brain and to trace cancer progression inside the gastrointestinal tract in mice with cellular resolution, respectively. These molecular and cellular imaging technologies provide us fundamental
insight into cancer research and help developing translational therapeutic strategies.
7. 문 의 : 기계항공공학부 이동준 교수 (djlee@snu.ac.kr)